Medication
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Preventing Antibiotic Resistance
Antibiotics are used to treat different types of bacterial infections. If your doctor has prescribed you an antibiotic, then it’s important that you take it and follow the dosing instructions provided to you. If you fail to take the antibiotic, miss a dose, or do not take it exactly as directed, chances are your infection will remain, worsen, or require you to be on antibiotics for an extended period of time until you’re able to get rid of the infection.
Common types of bacterial infections that antibiotics are used to treat include strep throat, ear infections, sinus infections, pneumonia, urinary tract infections, and skin infections. They work by preventing bacteria from multiplying as well as kill off bacteria. However, antibiotics won’t be effective in treating things like the common cold, influenza, chicken pox, measles, upset stomach or diarrhea – as these are often all viral in nature. It is possible to develop something like a sinus infection along with a common cold, however. If this is the case then you will still be required to take antibiotics – not for the cold itself, but for the infection.
When you fail to take antibiotics exactly as prescribed or take them unnecessarily (i.e. when you have a viral infection as opposed to a bacterial infection), you increase your risk of developing something known as antibiotic resistance. Antibiotic resistance occurs when bacteria becomes resistant to certain antibiotics used to treat them. The biggest concern that healthcare providers have when it comes to antibiotic resistance is that common infections, such as strep throat or pneumonia, which are usually easily treated, will eventually become untreatable in patients who overuse or abuse antibiotics. If you don’t take antibiotics as prescribed, bacteria can thrive and continue to spread. Along with not taking prescribed antibiotics properly, other examples of antibiotic misuse include giving your medication to others when it is not needed, or self-medicating with leftover antibiotics from prior bacterial infections. In the event that you did not finish your antibiotics (having been told to stop them by your family physician), then you should always return any unfinished medications to your pharmacy for proper disposal.
It’s also important to know how drug-resistant bacteria can be spread. Just like any bacterial infection, drug-resistant bacteria can also be spread from person-to-person (such as coughing, sneezing, or being exposed to bodily fluids), by touching contaminated surfaces (such as utensils, keyboards and doorknobs – and bacteria can survive on these types of surfaces for an extended amount of time.) It can also be spread through food, water and soil (i.e. meat, poultry, dairy products, and by drinking contaminated water), by having direct contact with certain animals (such as cats, dogs, reptiles, farm animals) and animal manure, as well as from international travel.
The best way to prevent antibiotic resistance is to use antibiotics responsibly. You can also take extra precautions to prevent illness. The best way to prevent illness is to ensure you practice good hygiene, such as washing your hands frequently (and properly!) with warm soap and water (as well as keeping them away from your eyes, nose and mouth), wiping down contaminated surfaces, and even practicing food safety – as food that is not prepared properly is one of the most common and easiest ways to develop food borne illness, such as food poisoning, e.coli, salmonella, etc.
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Medication Safety
The importance of understanding and adhering to medication safety protocols cannot be overstated, regardless of whether you take regular prescription medications or only need the occasional over-the-counter drug. These safety measures are fundamental yet vital, for the more informed you are about each medication you take, the better equipped you will be to manage your health effectively. Although most prescribed medications come with a detailed patient information sheet, it is not uncommon to have lingering questions about their proper usage. You might wonder about the correct way to take the medication, how frequently it should be administered, or if there are any unusual side effects you need to monitor. While you can certainly conduct a Google search to find answers to many of these questions, there is always the risk of running into information that is incorrect; therefore, it is preferable for patients to seek clarification directly from their prescribing physician or pharmacist. These healthcare professionals can provide personalized and accurate information that is crucial for safe medication use.
When it comes to taking medications, following the prescribed instructions precisely is of utmost importance unless your physician explicitly advises otherwise. For instance, if you have been prescribed a seven-day course of antibiotics, it is essential to complete the entire regimen, even if you begin to feel better before finishing the medication. Discontinuing the course prematurely or not taking the correct dosage can lead to a range of problems, including the recurrence of infections and the development of antibiotic resistance, which is a significant public health concern.
Before starting any new medication, it is crucial to inform your pharmacy of any other medications you are currently taking. This step is vital because certain prescription drugs can interact with one another, and some interactions can be dangerous, if not potentially fatal. Your pharmacist plays a key role in identifying possible drug interactions and can advise you accordingly. Should there be any conflicts between the medications you are prescribed and those you are already taking, a pharmacist can recommend safe and alternative medications for your doctor to consider prescribing.
It should be evident, but nonetheless, it bears repeating: never take a medication that has not been prescribed or specifically recommended to you by your physician. We often hear cautionary tales of individuals inadvertently taking drugs that are entirely different from what they believed they were consuming. For example, some medications might be contaminated with substances like Fentanyl, a potent synthetic opioid, which can be lethal even in minuscule amounts. Additionally, you might encounter medications that are expired or ones to which you have severe allergies. These scenarios underscore the necessity of obtaining medications only from trusted healthcare providers.
Moreover, it is imperative to store medications securely out of reach of children and pets. Both infants and animals are naturally curious and can easily crawl or climb to access areas where medications might be stored. To prevent accidental ingestion, medications should be kept in a hard-to-reach location or a locked cabinet. According to the Centers for Disease Control and Prevention (CDC), over 60,000 children are hospitalized annually due to accessing medications that were not adequately stored. If you suspect that your child has ingested any medication, it is critical to take them to the nearest emergency room immediately. For further guidance, you can contact the British Columbia Drug and Poison Information Centre (BC DPIC) at 604-682-5050 or toll-free at 1-800-567-8911. They provide a wealth of information, including a comprehensive list of prevention tips available on their website, which details proper medication storage techniques and actions to take in the event of an overdose or poisoning.
In addition to these precautions, many pharmacies participate in the BC Medications Return Program, established in 1996, which enables patients to return any unused or leftover medications. This program facilitates the safe disposal of medications and sharps, such as needles and syringes, thus preventing potential misuse and environmental harm. Participating in this program not only enhances community safety but also supports responsible medication management and environmental stewardship.
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Do You Need Antibiotics?
When you develop an illness, such as a viral infection (i.e. a common cold) or have a superficial wound (like a cut or scratch), these are things that will usually resolve on their own over a few days or couple of weeks, depending on the severity of your illness and the symptoms that you experience. If you have a viral infection, antibiotics will not help resolve your illness or speed up the recovery time. Taking an antibiotic when it is unnecessary to do so will potentially cause antibiotic resistance. However, during your recovery period, there are certain over-the-counter products that can purchase in order to help relieve symptoms. For example, a decongestant can help with symptoms related to a cold, while pain relief medications can help ease general body aches and pains and relieve fever if you have the flu; and Polysporin (which contains non-medicinal ingredients such as petrolatum, butylated hydroxytoluene, cocoa butter, cotton seed oil, olive oil, sodium pyruvate, and vitamin E) can help speed up the healing of wounds.
All of this being said, there are certain times in which you may develop a bacterial infection and require the use of antibiotics. Common infections that are caused by bacteria include:
• Lower and upper respiratory infections, including pneumonia, sinus infections as well as ear infections, and strep throat.
• Urinary tract infections, such as bladder and kidney infections.
• Food poisoning caused by E.coli.The type of antibiotic you need to be prescribed depends on the type of infection you have. For example, either Penicillin or amoxicillin are typically the number one choice in antibiotics used to treat group A strep pharyngitis (strep throat.) If you are diagnosed with pneumonia, then Macrolide drugs such as Azithromycin or Clindamycin are the preferred treatment choices; while Amoxicillin and Azithromycin can both also be used for the treatment of sinus and ear infections, in addition to others.
If your doctor prescribes an antibiotic to you, then they are weighing the benefits vs. risks, though some antibiotics may have interactions with other medications you’re taking (which may require you to temporary stop said medications, if it is safe for you to do so) as well as food, which your pharmacy will notify you of. Many antibiotics also come with several side effects – most commonly things like nausea, upset stomach, and diarrhea. These symptoms can often be reduced if you eat a small meal or drink milk (which helps coat the stomach) at least 30 minutes before taking the antibiotic. However, some antibiotics can also be taken with or without food. How an antibiotic will affect an individual simply varies from person to person. One antibiotic that might make you feel sick may not make another person who takes it feel sick.
In addition to this, it’s important to take your antibiotic exactly as prescribed. For example, if you have been instructed to take your antibiotic twice a day, this typically means that it should be taken morning and night (i.e. 7 AM and 7 PM.) Failing to take your antibiotic exactly as your doctor has prescribed could result in your infection persisting or worsening, and you may ultimately require a longer course of the antibiotic, or need to be switched to a different antibiotic all together.
It’s also possible to be allergic to an antibiotic. While the most common antibiotic that people tend to be allergic to is Penicillin, you can be allergic to any antibiotic. An allergic reaction from taking an antibiotic can be mild (including things like rash or hives), while an allergic reaction can also be severe (including things like swelling of the lips and tongue, swelling of the throat, and trouble breathing – also known as anaphylaxis.) If you allergy is mild, you can find relief by taking an anti-histamine. However, if your allergy is severe, you will likely need an injection of epinephrine. In the event of a serious allergy, you should always call 911 as it can quickly turn into a life-threatening situation.
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Medication Side Effects
The pivotal role of medications in the management and treatment of a diverse spectrum of health conditions is irrefutable. However, alongside their therapeutic benefits, these pharmaceutical agents often bring with them a suite of side effects. These effects range from the mildly inconvenient to the profoundly impactful, persisting over extended periods. This article aims to meticulously explore the array of common side effects associated with medication use, delving into strategies for their management, all the while upholding the epitome of medical professionalism and embedding the principles of patient-centred care at the core of our discussion.
Common Medication Side Effects
The journey of medications, tailored to address specific health anomalies, sometimes inadvertently transcends beyond their targeted path, culminating in side effects. These side effects are as varied as the individuals who experience them, influenced by a constellation of factors such as age, gender, health status, and the simultaneous use of other medications. These side effects are categorically diverse, encompassing gastrointestinal issues like nausea, vomiting, diarrhoea, and constipation; central nervous system-related challenges including dizziness, headache, and somnolence; dermatological reactions manifesting as rashes and itching; and cardiovascular concerns, which may include palpitations and fluctuations in blood pressure.
Gastrointestinal Side Effects
Among the myriad of side effects, gastrointestinal ones stand out in prevalence. Medications, particularly chemotherapy agents and antibiotics, can induce nausea and vomiting, yet these can be mitigated through strategic approaches. Employing antiemetic medications and ingesting these pharmaceuticals alongside food, except when contraindicated, offers relief. Constipation, a common issue with opioid analgesics and certain anticholinergic drugs, necessitates a multifaceted management strategy. This strategy encompasses dietary modifications to bolster fibre intake, ensuring adequate hydration, and judicious use of laxatives, strictly under medical supervision.
Central Nervous System-Related Side Effects
Central nervous system-related side effects such as dizziness, headaches, and somnolence can profoundly impinge upon an individual’s quality of life and their ability to perform daily tasks. Managing these effects requires a nuanced approach, including careful dose adjustments and strategic scheduling of medication intake. This scheduling is crucial for minimizing disruption – for instance, taking sedating medications at night. Beyond pharmacological interventions, embracing non-pharmacological methods, notably relaxation techniques for headache relief, is advisable. Patients experiencing these symptoms are strongly cautioned against engaging in activities that demand high levels of alertness, such as operating machinery or driving, until they have fully acclimatized to the effects of the medication.
Dermatological Reactions
Dermatological reactions, while often not life-threatening, can cause considerable distress to patients. Manifestations such as rashes, pruritus (itching), and urticaria (hives) could indicate an allergic reaction to a medication, necessitating an immediate cessation of the offending agent and consultation with a healthcare professional. For mild reactions, the use of topical corticosteroids or oral antihistamines may provide symptomatic relief. However, it’s imperative to recognize and promptly address severe reactions, such as Stevens-Johnson syndrome, which require urgent medical intervention.
Cardiovascular Side Effects
The cardiovascular side effects of medications, particularly palpitations or alterations in blood pressure, necessitate vigilant monitoring and astute management due to their potential to escalate into severe conditions. For instance, the administration of antihypertensive drugs can lead to hypotension, demanding a careful, gradual dose titration and consistent blood pressure monitoring. Patients receiving these medications are advised to transition slowly from sitting or lying positions to mitigate the risk of orthostatic hypotension. On the other hand, medications that may elevate blood pressure, such as certain non-steroidal anti-inflammatory drugs (NSAIDs), require frequent blood pressure assessments and potential modifications in the therapeutic regimen.
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Antibiotic Awareness
In the ever-evolving journey of modern medicine, antibiotics have emerged as both a beacon of hope and a subject of intense scrutiny. As we delve into the complexities of their application, it becomes crucial to understand the dichotomy of their usage — discerning precisely when these potent medications are required and when restraint must be exercised.
The discovery of antibiotics, heralded by Alexander Fleming’s serendipitous encounter with penicillin in 1928, revolutionized the medical field. These drugs are specifically designed to combat bacterial infections, either by killing bacteria or inhibiting their growth. The success of antibiotics in treating a plethora of bacterial diseases is indisputable. From life-threatening conditions such as sepsis to more common infections like strep throat, antibiotics have saved countless lives and continue to be a cornerstone of modern healthcare.
The Misconception of Antibiotics
Despite their remarkable efficacy, antibiotics are not a one-size-fits-all solution. They are ineffective against viruses, such as those causing the common cold, influenza, or COVID-19. Viruses are fundamentally different from bacteria; they require a host to replicate and do not possess the structures targeted by antibiotics. Therefore, prescribing antibiotics for viral infections is not only futile but can also be detrimental.
The misuse and overuse of antibiotics have led to the emergence of antibiotic-resistant bacteria, a global health threat that undermines the efficacy of these critical drugs. This resistance occurs when bacteria mutate and survive exposure to an antibiotic, subsequently multiplying and passing on these resistant traits. The result is a dwindling arsenal against infections that were once easily curable.
Discerning the Need for Antibiotics: A Clinical Perspective
Medical professionals in Canada, like elsewhere, adhere to evidence-based guidelines when considering antibiotic prescriptions. The decision is multifaceted, relying on clinical diagnosis, laboratory results, and patient-specific factors.
- Bacterial Infections: Clear indications for antibiotic therapy include confirmed bacterial infections like urinary tract infections (UTIs), bacterial pneumonia, and cellulitis. These conditions, if left untreated, can lead to severe complications or become life-threatening.
- Severity and Site of Infection: Severe infections, particularly those that are systemic or occur in deep tissues, often necessitate antibiotic intervention. For example, osteomyelitis, an infection of the bone, requires antibiotics to prevent the spread of infection and preserve the integrity of the skeletal system.
- Patient Vulnerability: Immunocompromised individuals, such as those undergoing chemotherapy or living with HIV/AIDS, may require antibiotics to treat or prevent infections that their bodies would otherwise struggle to combat.
When Antibiotics Are Not Warranted
Conversely, antibiotics should not be used indiscriminately. Conditions such as bronchitis, sinusitis, and ear infections often resolve without antibiotic therapy, especially when they are viral in origin. In these cases, supportive care is paramount. Moreover, the symptomatic relief of mild bacterial infections can sometimes be achieved through alternative means. For example, the body’s immune system can often clear a mild ear infection without the need for antibiotics.
Patients also play a pivotal role in antibiotic stewardship. It is essential to complete prescribed antibiotic courses to prevent the survival of partially resistant bacteria. However, patients should not pressure healthcare providers for antibiotics when they are not indicated, nor should they self-medicate with leftover prescriptions or medications obtained without proper medical consultation.
The Future of Antibiotics
Ongoing research and development are critical to surmount the challenge of antibiotic resistance. The medical community is exploring new classes of antibiotics, alternative therapies, and innovative approaches to treating bacterial infections.
The landscape of antibiotics is one of balance and precision. In the realm of medicine, particularly within the Canadian healthcare system, the call to action is clear — antibiotics are a precious commodity to be used judiciously, with a focus on both individual patient care and the broader implications for public health. As we navigate this terrain, it is the collective responsibility of healthcare providers and patients alike to ensure that antibiotics retain their efficacy for generations to come.
While antibiotics remain a fundamental component of modern medicine, their use must be tempered with knowledge and caution. Understanding when antibiotics are required and when they are not is paramount in safeguarding their effectiveness for the future.
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Protecting British Columbia’s Supply of Ozempic
The government of British Columbia is taking essential measures to ensure that individuals with diabetes in the province have uninterrupted access to the crucial medication Semaglutide, sold under the brand name Ozempic. This decision comes amidst growing concerns about potential shortages due to increased demand for the drug in various regions. Ozempic, which is an injectable prescription medication intended for the treatment of Type 2 diabetes mellitus, contains the active ingredient Semaglutide. As of now, B.C. has not faced any shortages of the drug. However, PharmaNet data from the province reveals an unusually high proportion of Ozempic dispenses being purchased by United States patients from B.C.-based pharmacies.
U.S. consumers are increasingly turning to Canadian pharmacies for more affordable drug prices. Pharmacies in B.C. can fill prescriptions for patients written by U.S. doctors if co-signed by a Canadian practitioner. In January and February 2023, 15,798 dispenses of Ozempic, accounting for 15% of the total, were sold to U.S. residents, who comprised 19% (12,816) of all patients receiving the drug from a pharmacy in the province. In contrast, the average percentage of other medications sold to Americans is only 0.4%. PharmaNet data shows that two B.C. pharmacies accounted for 13,197 of the 15,798 dispenses to U.S. residents in January and February 2023, which represents 88% of all such dispenses. Of these prescriptions, 95% were issued by one or more prescribers identifying themselves as practitioners from Nova Scotia.
Health Minister Adrian Dix clarified that the primary objective of procuring Ozempic for B.C. is to ensure its availability for local and Canadian patients in need of the medication to manage their Type 2 diabetes. Consequently, the province is taking appropriate action to guarantee continued access to the drug for its residents. To safeguard the supply of Ozempic for B.C. and Canadian citizens, the provincial government plans to modify regulations, restricting sales or dispensing of the drug to non-Canadian residents in cases of potential supply issues.
BC PharmaCare offers limited coverage for Ozempic as a secondary treatment for Type 2 diabetes, helping patients control their blood sugar levels when metformin, another diabetes medication, proves ineffective. Ozempic is not approved for weight loss. Due to the substantial dispensing volumes, the Ministry of Health has requested that relevant colleges ensure compliance with the approved indication for Ozempic by physicians and pharmacies, in addition to meeting the colleges’ clinical practice requirements for prescribing and dispensing medications.